VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Pig

Scientific Name: Sus scrofa domestica

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Artiodactyla-> Suina-> Suidae-> Sus-> Sus scrofa

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Hepacivirus C

Family: Flaviviridae

Receptor: LDLR

Receptor LDLR information

Summary: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_0046 2021.04 10X Genomics Lung Normal 21981 Link
Vthunter_0069 2021.04 10X Genomics Frontal Normal 8812 Link
Vthunter_0070 2021.04 10X Genomics Occipital Normal 6829 Link
Vthunter_0071 2021.04 10X Genomics Parietal Normal 6162 Link
Vthunter_0072 2021.04 10X Genomics Hypothalamus Normal 7302 Link
Vthunter_0073 2021.04 10X Genomics Temporal Normal 3145 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_0074 2021.04 iDrop Lung Normal 13580 Link
Vthunter_1013 2019.12 10X Genomics Lung Normal 7465 Link
Vthunter_1014 2019.12 10X Genomics Lung Normal 3987 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of LDLR in human tissues   [NCBI]

Expression: Ubiquitous expression in adrenal (RPKM 29.0), lung (RPKM 28.5) and 25 other tissues?

Protein expression of LDLR in human tissues   [Proteinatlas]